Knox was sentenced to 28 years and six months while Sollecito was sentenced to 25 years.
Miss Kercher's sister Stephanie and brother Lyle were both at the Nuovo Palazzo di Giustizia courthouse in Florence to hear the outcome.
Knox, 26, and Sollecito, 29, were originally charged in 2007 after Miss Kercher was found semi-naked with her throat cut in the bedroom of her house in Perugia, Italy.
She was sentenced to 26 years and Sollecito to 25 years but in 2011 the verdicts were overturned and both walked free.
The retrial began last September in Florence, 100 miles from where the murder took place. More
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